Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1
نویسندگان
چکیده
منابع مشابه
Triptolide induces apoptotic cell death of multiple myeloma cells via transcriptional repression of Mcl-1.
Triptolide, a diterpenoid trioxide purified from the Chinese herb Tripterygium wilfordii Hook F, has been used as a natural medicine in China for hundreds of years. Several reports have demonstrated that triptolide inhibits the proliferation of cancer cells in vitro and reduces the growth of several types of tumors in vivo. To address the potential of triptolide as a novel therapeutic agent for...
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formation and evolution of regional organizations: the case study of the economic cooperation organization (eco)
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15 صفحه اولCurcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α
BACKGROUND Curcumin has been used as an alternative medicine for the treatment of infantile hemangiomas (IHs); however, the mechanism underlying the effectiveness of curcumin in IHs remains largely unclear. METHODS In this study, we isolated primary human hemangioma endothelial cells (HemECs) from fresh surgical specimens of 3 patients. We treated HemECs by curcumin and investigated the alter...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2012
ISSN: 0887-6924,1476-5551
DOI: 10.1038/leu.2012.19